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英文名: 8-azaguanine,8-AzaG, Guanazolo
中文名: 8-氮鸟嘌呤; 5-氨基-7-羟基-1H-连三唑骈（－d－）嘧啶
产品说明:5-氨基-7-羟基-1H-连三唑骈（－d－）嘧啶。是碱基类似物之一。已知它是鸟便嘌呤的代谢抑制物，对细胞发育起阻碍作用。给予鸟嘌呤或鸟苷则可解除阻碍作用。一般认为一当纳入核酸便显示阻碍作用，但它也对嘌呤核苷酸生物合成阶段起阻碍作用。
SIGMA产品相关资料:
Sigma A5284 8-Azaguanine
Hybri-Max™, lyophilized powder, γ-irradiated, hybridoma tested
Synonym: 2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, 8-AzaG, Guanazolo
CAS Number: 134-58-7
Linear Formula: C4H4N6O
Molecular Weight: 152.11
Beilstein Registry Number: 171098
EC Number: 205-148-1
MDL number: MFCD00056937
PubChem Substance ID: 24890963
Description
Related Keywords 8-Azaguanine resistance, AGR resistant cell selection, sporulation inhibitor, guanine analog.
Application For use in hybridoma cell culture applications as a myeloma selection agent.
Reconstitution Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium. Final working concentration: 130 μM 8-azaguanine.
Legal Information Hybri-Max is a trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co.
Properties
grade Hybri-Max
sterility γ-irradiated
form lyophilized powder
mp >300 °C(lit.)
suitability hybridoma tested
storage temp. −20°C
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