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英文名称: Melatonin
产品别名: 松果体素，褪黑色素; N-乙酰基-5-甲氧基色胺, 褪黑素
外观: 白色结晶或白色结晶性粉末
Sigma相关产品资料：
Sigma M5250 Melatonin
powder, ≥98% (TLC)
Synonym: N-Acetyl-5-methoxytryptamine
CAS Number: 73-31-4
Linear Formula: C13H16N2O2
Molecular Weight: 232.28
Beilstein Registry Number: 205542
EC Number: 200-797-7
MDL number: MFCD00005655
PubChem Substance ID: 24278103
Description
Caution Solutions are light sensitive and subject to oxidation.
Biochem/physiol Actions Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
性质
assay ≥98% (TLC)
form powder
color off-white
mp 116.5-118 °C(lit.)
solubility H2O: 0.1 mg/mL
ethanol: 8 mg/mL
Gene Information human ... MTNR1A(4543), MTNR1B(4544), NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
storage temp. −20°C |