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中文名称: 姜黄素,姜黄色素
英文名称: Curcumin,Turmeric yellow, Diferuloylmethane , 1,6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-
说明: 姜黄素可用来抗菌,解毒,为橙黄色结晶粉末，味稍苦。不溶于水，溶于乙醇、丙二醇，易溶于冰醋酸和碱溶液，在碱性时呈红褐色，在中性、酸性时呈黄色。对还原剂的稳定性较强，着色性强(不是对蛋白质)，一经着色后就不易退色，但对光、热、铁离子敏感，耐光性、耐热性、耐铁离子性较差。
Sigma相关产品资料：
Sigma C7727 Curcumin
≥94% (curcuminoid content), ≥80% (Curcumin)
Synonym: Diferuloylmethane, Diferulylmethane, Natural Yellow 3, (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
CAS Number: 458-37-7
Linear Formula: [HOC6H3(OCH3)CH=CHCO]2CH2
Molecular Weight: 368.38
Colour Index Number: 75300
Beilstein Registry Number: 2306965
EC Number: 207-280-5
MDL number: MFCD00008365
PubChem Substance ID: 24892983
Description
Biochem/physiol Actions A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
Properties
vapor density 13 (vs air)
assay ≥80% (Curcumin)
≥94% (curcuminoid content)
solubility ethanol: 1 mg/mL
DMSO: 11 mg/mL
0.5 M NaOH: soluble (then immediately diluted in PBS)
Gene Information human ... APP(351), CYP1A2(1544)
storage temp. −20°C
Safety
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 2
RTECS MI5230000 |