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Streptozocin
≥75% α-anomer basis, ≥98% (HPLC), powder DOWNLOAD MSDS (PDF)
Synonym: N-(Methylnitrosocarbamoyl)-α-D-glucosamine Streptozotocin
CAS Number 18883-66-4
Empirical Formula (Hill Notation) C8H15N3O7
Molecular Weight 265.22
assay ≥75% α-anomer basis
≥98% (HPLC)
form powder
color white to off-white
mp 121 °C (dec.)(lit.)
storage temp. −20°C
Frequently Asked Questions
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Application
Streptozocin is used to induce Type 1 diabetes for medical research.
General description
Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Streptozocin, a diabetagen, is especially toxic to pancreatic islet insulin-producing β-cells. It is toxic to GLUT2 positive neuroendocrine tumor cells. |