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Recombinant Human KGF (FGF-7)
Catalog Number: 100-19
Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7
Description: Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues.
AA Sequence: CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT
Source: E.coli
Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
Cross Reactivity: Mouse, Rat, Human, Leech, N/A
Country of Origin: USA |