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Recombinant Human PlGF-1
Catalog Number: 100-06
Synonyms: Placenta Growth Factor-1, PIGF, PGF
Description: PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 132 amino acid polypeptide chains.
AA Sequence: MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR
Source: E.coli
Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to chemoattract human monocytes of using a concentration range of 1.0-10.0 ng/ml.
Cross Reactivity: Human, Mouse
Country of Origin: USA |