Wnt Antagonist II, IWP-2 Inhibitor of Wnt Production-2, Wnt Pathway Inhibitor II, Porcn Inhibitor I A cell-permeable benzothiazolyl-acetamide compound that inhibits the cellular Wnt processing and secretion via selective blockage of MBOAT (membrane-bound O-acyltranferase) family member Porcn- (Porcupine) mediated Wnt palmitoylation. IWP-2 does not affect Wnt/β-catenin signaling pathway in general and, unlike IWR-1-endo (Cat. No. 681669), displays no effect against Wnt-stimulated cellular responses. Also available as a 10 mM solution in DMSO (Cat. No. 506072). 产品信息 Form Off-white solid Molar mass 466.6 Protect from Light 是的 Packaged under inert gas 是的 Purity ≥97% by HPLC Solubility DMSO or EtOH Chemical formula C22H18N4O2S CAS number 686770-61-6 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Harmful