VEGF Inhibitor, Je-11 A dimerized peptide derived from the third Ig-like domain of the human vascular endothelial growth factor receptor-2 (VEGFR-2 or KDR/Flk-1) comprising residues 247 - 261. Acts as an inhibitor of VEGF-stimulated autophosphorylation of VEGFR-2 and inhibits the proliferation and migration of cultured microvascular endothelial cells. Binds to VEGF and blocks its interaction with VEGFR-2 (IC50 = 500 nM on extracellular VEGFR-2 fragments; IC50 = 30 µM on HUVEC). 产品信息 Peptide Sequence (H-Arg-Thr-Glu-Leu-Asn-Val-Gly-Ile-Asp-Phe-Asn-Trp-Glu-Tyr-Pro-Ala-Ser)2-Lys-NH2 Form White lyophilized solid Formulation Supplied as a trifluoroacetate salt. Molar mass 4131.5 Hygrocopic 是的 Packaged under inert gas 是的 Purity ≥90% by HPLC Solubility DMSO Chemical formula C188H273N49O57 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Standard Handling