TUNICAMYCIN, STREPTOMYCES LYSOSUPERFICUS

Tunicamycin, Streptomyces lysosuperficus
A nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells. Also available as a 25 mM solution in DMSO (Cat. No. 504570).
产品信息
Form  White to off-white solid
Primary Target  N-linked glycosylation
Secondary target  thrombin-induced Ca2+ mobilization in cells
Molar mass  844.9
Purity  ≥98% by HPLC (A+B+C+D)
Reconstitution  Aqueous solutions can be prepared from stock solutions in DMSO by diluting with H2O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0 (preferably >8.0).
Solubility  DMF, DMSO, or Pyridine
Chemical formula  C39H64N4O16
RTECS  YO7980200
CAS number  11089-65-9
Merck USA index 14, 9819
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage  +15°C to +30°C
Ship  Ambient Temperature Only
Highly Toxic & Carcinogenic / Teratogenic