产品信息: Form White solid Primary Target PDE IV Primary Target IC50 800 nM Secondary target NF-κB and NFAT activation in Jurkat and primary T cells Cell permeable 是的 Purity ≥98% by HPLC Chemical formula C16H21NO3 RTECS UY5749237 CAS number 61413-54-5 Merck USA index 14, 8251 Storage +2°C to +8°C Ship Ambient Temperature Only Irritant 产品说明: A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 800 nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-κB and NFAT activation in Jurkat and primary T cells.