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产品说明
A phenolic product found in both grape skins and wines. Has antifungal, antitumor, and antioxidative properties. A specific inhibitor of cyclooxygenase-1 (COX-1; ED50 = 15 µM). Also inhibits the hydroxyperoxidase activity of COX-1 (ED50 = 3.7 µM). Strongly inhibits insoluble transthyretin (TTR) amyloid fibril formation. Inhibits phorbol ester-induced free radical formation in HL-60 cells (ED50 = 27 µM) and acts as an anti-mutagenic agent (ED50 = 15 µM) in TM677 cells treated with DMBA. Also a selective inhibitor of P450 1A1. Reported to activate sirtuins and promote the survival of eukaryotic cells.
产品信息
Form Off-white solid
Primary Target COX-1
Primary Target IC50 ED50 = 15 µM
Secondary target hydroxyperoxidase activity of COX-1 (ED50 = 3.7 µM), insoluble transthyretin (TTR) amyloid fibril formation, phorbol ester-induced free radical formation in HL-60 cells (ED50 = 27 µM), acts as an anti-mutagenic agent (ED50 = 15 µM) in TM677 cells treated with DMBA.,inhibitor of P450 1A1
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥98% by TLC
Chemical formula C14H12O3
CAS number 501-36-0
Merck USA index 14, 8158
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |