RAP, HUMAN, RECOMBINANT {E. COLI}

RAP, Human, Recombinant, E. coli
Receptor Associated Protein
Recombinant, human RAP fused to GST, expressed in E. coli, and subsequently cleaved with thrombin to remove GST. Antagonizes the ligand binding of certain members of the low-density lipoprotein receptor family such as low density lipoprotein receptor-related protein (LRP) and very low-density lipoprotein (VLDL) receptor. Promotes the proper folding and subsequent exocytic trafficking of the wild-type low density lipoprotein receptor (LDLR) and several of its class 2 mutants. Expressed as a GST-fusion protein that is subsequently cleaved with thrombin. Typical concentrations to block LRP or VLDL receptor are 200-300 nM. For antagonism of LDLR, 1 µM is recommended.
产品信息
Form  Liquid
Formulation  150 mM NaCl, 100 mM Tris-HCl, pH 7.4.
Molar mass  39000
Avoid freeze/thaw  是的
Purity  ≥90% by SDS-PAGE
商店和运输信息
Storage  ≤ -70°C
Ship  Dry Ice Only
Standard Handling