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Protein Synthesis Initiation Inhibitor, NSC 119889
3,4,5,6-Tetrabromofluorescein
A cell-permeable, xanthenyl compound that prevents mRNA-ribosome interaction and inhibits 5’-mediated/cap-dependent initiation of protein synthesis (>95% inhibition at 50 µM in in vitro translation assays using Krebs, rabbit reticulocyte, or E. coli S30 extract).
产品信息
Form Light brown solid
Primary Target human arginine methyl transferase
Primary Target IC50 1.41 µM
Secondary target IC50 = 780 nM yeast arginine methyl transferase
Molar mass 647.9
Protect from Light 是的
Cell permeable 是的
Purity ≥95% by HPLC
Solubility DMSO or MeOH
Chemical formula C20H8Br4O5
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Irritant |