PROTEINASE 3, HUMAN NEUTROPHILS

Proteinase 3, Human Neutrophils
Myoblastin, PR3, PR3 Ag, PR III
Native, human proteinase 3 purified from neutrophils. A serine protease with proinflammatory properties, expressed mainly in neutrophils. Proteinase 3 is the antigen for anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, frequently found in Wegener's granulomatosis.
产品信息
Form  Liquid
Formulation  In 150 mM NaCl, 50 mM sodium acetate, 0.1% Triton® X-100 detergent, pH 6.0.
Molar mass  23000
Avoid freeze/thaw  是的
Unit definition  One unit is defined as the amount of enzyme that will hydrolyze one µmol methoxysuccinyl-Ala-Ala-Pro-Val-pNA per min at 37°C, pH 7.5.
Purity  ≥96% by SDS-PAGE
Source  Prepared from neutrophils that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
商店和运输信息
Storage  -20°C
Ship  Blue Ice Only
Standard Handling