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16,16-Dimethyl Prostaglandin E2
9-Oxo-11α,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid, dmPGE2
A cell-permeable and orally available synthetic PGE2 (Cat. No. 538904) 16,16-dimethyl derivative that exhibits similar biological activity as PGE2 as an EP receptor agonist both in in vitro and in in vivo, while being more resistant to PGDH metabolism. Shown to amplify wnt activity through cAMP/PKA-mediated regulation of cellular β-catenin protein stability during vertebrate development and organ regeneration.
产品信息
Form Liquid
Formulation Supplied as a solution in methylacetate (1 mg/100 µL)
Molar mass 380.5
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥95% by HPLC
Solubility DMSO or EtOH
Chemical formula C22H36O5
CAS number 39746-25-3
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage ≤ -70°C
Ship Dry Ice Only
Flammable |