|
Platelet Membrane Glycoproteins, IIbIIIa, Human Platelets
GPIIbIIIa, Fibrinogen Receptor, CD41/CD61
Native, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds to fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbα and GPIIbβ, whereas GPIIIa has only one polypeptide chain.
产品信息
Form Liquid
Formulation In 100 mM NaCl, 20 mM Tris-HCl, 1 mM CaCl2, 50% glycerol, 0.1% TRITON® X-100 Detergent, ≤0.1% sodium azide, pH 7.4.
Source Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
商店和运输信息
Storage ≤ -70°C
Ship Dry Ice Only
Standard Handling |