PARP Inhibitor VIII, PJ34 A cell-permeable, water-soluble phenanthridinone-derivative that acts as a potent inhibitor of poly(ADP-ribose) polymerase (PARP; EC50 = 20 nM). Shown to be about 10,000 times more potent than the prototypical PARP inhibitor, 3-Aminobenzamide (Cat. No. 165350; EC50 = 200 µM). Does not act as an antioxidant at higher concentrations (1 µM to 10 mM). Exhibits neuroprotection in in vivo and in vitro models of stroke. Also available as a 20 mM solution in H2O(Cat. No. 528151). 产品信息 Form White solid Primary Target PARP Primary Target IC50 EC50 = 20 nM Molar mass 331.8 Protect from Light 是的 Hygrocopic 是的 Packaged under inert gas 是的 Cell permeable 是的 Purity ≥98% by HPLC Solubility H2O Chemical formula C17H17N3O2 · HCl CAS number 344458-15-7 商店和运输信息 Storage -20°C Ship Ambient Temperature Only Standard Handling