|
PIH
pyridoxal isonicotinoyl hydrazone, Iron Chelator III
A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class. Even at low concentrations, highly effective in mobilizing Fe3+ from cells and preventing its uptake from transferrin, even at low concentrations. Exhibits similar specificity and binding affinity as Deferoxamine Mesylate (Cat. No. 252750) but has greater access to mitochondrial iron. Also useful for the management of iron overload disease in experimental models. Inhibits the induction of heme containing indoleamine 2,3-dioxygenase activity.
产品信息
Form Yellow solid
Molar mass 286.3
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥99% by HPLC
Solubility DMSO or slightly acidic medium
Chemical formula C14H14N4O3
CAS number 737-86-0
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |