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Pertussis Toxin, Bordetella pertussis, Glycerol Solution
Islet-activating Protein
A protein endotoxin that catalyzes ADP-ribosylation of guanine nucleotide-binding regulatory proteins. The holotoxin has five dissimilar subunits S-1, S-2, S-3, S-4, and S-5, in a molar ratio of 1:1:1:2:1, S-1 (A protomer) is responsible for the enzymatic activity of the toxin, and S-2, S-3, S-4, and S-5 form the B oligomer which is responsible for the toxins binding to the cell surface. NOTE: This product is not activated, hence for use in cell-free systems, activation is required.
产品信息
Form Liquid
Formulation In 500 mM NaCl, 50 mM Tris, 10 mM glycine, 50% glycerol, pH 7.5.
Activity ≤35 pmol/min/µg in the presence of 1 µM calmodulin
Biological activity ≤1 ng/ml as determined in a clustering assay using CHO cells line
Purity Five distinct bands by SDS-PAGE
Contaminants Adenylate cyclase.
RTECS XW5883750
CAS number 70323-44-3
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage -20°C
Ship Blue Ice Only
Toxic
Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada. |