PASTEURELLA MULTOCIDA TOXIN

Pasteurella Multocida Toxin, Pasteurella multocida
A bacterial protein toxin that binds to and enters eukaryotic cells via receptor-mediated endocytosis. Acts intracellularly to initiate the inositol trisphosphate signaling pathway, Ca2+ mobilization, and DNA synthesis. Stimulates tyrosine phosphorylation of multiple substrates including focal adhesion kinase. Exerts its action on the α-subunit of the Gq family of G-proteins. Has been used for the activation of Gq-protein-coupled phosphatidylinositol-specific phospholipase C (PLC) in intact cells, making PMT useful as a tool for studying Gq-linked signal transduction.
产品信息
Form  Lyophilized solid
Formulation  Lyophilized from 100 mM NaCl, 30 mM Tris, 0.1% sucrose, pH 8.3.
Molar mass  143000
Purity  Single band by SDS-PAGE
Solubility  H2O
CAS number  129876-91-1
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage  -20°C
Ship  Ambient Temperature Only
Toxic
Canadian export regulations  Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.