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Pam3Cys-Ser-(Lys)4, Hydrochloride
(S)-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH, 3HCl, P3CSK4, 3HCl, Pam3Cys-SK4, 3HCl
A cell-permeable, water-soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Induces the release of IL-1, IL-6, TNF-α, superoxide, and NO. Promotes the translocation of NF-κB, enhances tyrosine protein phosphorylation and activation of ERK1/2 and MEK1/2. Acts as a selective agonist of TLR2 (Toll-like receptor 2).
产品信息
Form Lyophilized solid
Molar mass 1619.6
Protect from Moisture 是的
Purity ≥90% by HPLC
Solubility H2O
Chemical formula C81H156N10O13S • 3 HCl
商店和运输信息
Storage -20°C
Ship Blue Ice Only
Standard Handling |