p75NTR Signaling Inhibitor, Cell-permeable, TAT-Pep5 TAT-Pep5, H-YGRKKRRQRRR-CFFRGGFFNHNPRYC-OH, Cyclic The p75NTR inhibitor Pep5 (Cat. No. 506180) is made cell-permeable by fusing it with the N-terminal protein transduction domain sequence (11 amino acids) from HIV protein TAT. Shown to act as an effective blocker of MAG- and Nogo-induced inhibition of neurite outgrowth in both DRG (dorsal root ganglion) and postnatal cerebellar neurons. A potential therapeutic agent against inhibition of regeneration in the central nervous system. 产品信息 Peptide Sequence H2N-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys¹2-Phe-Phe-Arg-Gly-Gly-Phe-Phe-Asn-His-Asn-Pro-Arg-Tyr-Cys26-OH disulfide bond (12-26) Form Lyophilized solid Formulation Supplied as a trifluoroacetate salt. Molar mass 3404.9 Protect from Light 是的 Hygrocopic 是的 Packaged under inert gas 是的 Purity ≥95% by HPLC Solubility DMSO Chemical formula C150H227N57O32S2 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Standard Handling