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产品说明
An eight residue peptidomimetic, tight binding transition-state analog inhibitor of human brain memapsin 2 (Ki = 1.6 nM, recombinant memapsin 2; Ki = 9.58 nM, recombinant pro-memapsin 2). Also inhibits cathepsin D (Ki = 48 nM). This aspartyl protease inhibitor is designed from the template of the β-secretase site of Swedish β-amyloid precursor protein (APP) with Asp to Ala replacement; also includes a nonhydrolyzable hydroxyethylene isostere between Leu and Ala.
产品信息
Form Liquid
Formulation A 1 mM (250µg in 280 µl) solution in DMSO. Supplied as a trifluoroacetate salt.
Primary Target human brain memapsin 2
Primary Target Ki 1.6 nM, recombinant memapsin 2
Secondary target Ki = 9.58 nM, recombinant pro-memapsin 2, also inhibits cathepsin D (Ki = 48 nM)
Protect from Light 是的
Protect from Moisture 是的
Packaged under inert gas 是的
Purity ≥90% by HPLC
Chemical formula C41H64N8O14
CAS number 314266-76-7
Storage -20°C
Ship Ambient Temperature Only
Standard Handling |