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NSC 721648
5-Fluoro-2-(3,4-dimethoxyphenyl)benzothiazole, GW 610; PMX 610
A cell-permeable benzothiazole compound that exhibits potent in vitro antiproliferative activity against HCC 2998, IGROV1, MCF-7, MDA 468, SR, and T-47D (GI50 <1 nM), while showing much reduced effect against 50 other human tumor cells in a panel screening. Although it is a high affinity AhR ligand (IC50 = 25 nM; Ki = 6.8 nM in a TCDD competitive binding study) and a known CYP1A1 inducer, neither property can fully account for its antitumor activity.
产品信息
Form White crystalline solid
Molar mass 289.3
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥97% by HPLC
Solubility DMF or DMSO
Chemical formula C15H12FNO2S
CAS number 872726-44-8
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |