NIPP-1, HISTAG, BOV. THYMUS, RECOM

NIPP-1, His•Tag®, Bovine Thymus, Recombinant, E. coli
Nuclear Inhibitor of Protein Phosphatase-1
Recombinant, bovine NIPP-1 fused to a His•Tag® sequence and expressed in E. coli. Potent and specific inhibitor of protein phosphatase 1 (PP1; Ki = 1-10 pM) that can be used to distinguish PP1 from other major serine/threonine protein phosphatases including PP2A, PP2B, and PP2C. Also an ideal substrate for protein kinase A and casein kinase II. Thought to be involved in the targeting of PP1 to RNA-associated substrates and may also be involved in the dephosphorylation of transcription factors like CREB and the tumor suppressor Rb.
产品信息
Form  Liquid
Formulation  In 500 mM NaCl, 20 mM Tris, 500 µM benzamidine, 500 µM PMSF, 5 µM leupeptin, pH 7.5.
Primary Target  PP1
Primary Target Ki  1-10 pM
Molar mass  38500
Avoid freeze/thaw  是的
Purity  ≥90% by SDS-PAGE
商店和运输信息
Storage  -20°C
Ship  Dry Ice Only
Standard Handling