产品说明 A cell-permeable quinazoline compound that acts as a highly potent inhibitor of NF-κB transcriptional activation (IC50 = 11 nM in Jurkat cells) and LPS-induced TNF-α production (IC50 = 7 nM in murine splenocytes). Shown to exhibit anti-inflammatory effect on carrageenin-induced paw edema in rat. A 10 mM (1 mg/281 µl) solution of NF-κB Activation Inhibitor (Cat. No. 481407) in DMSO is also available. 产品信息 Form Off-white solid Primary Target NF-κB transcriptional activation Primary Target IC50 11 nM in Jurkat cells Secondary target LPS-induced TNF-α production (IC50 = 7 nM in murine splenocytes) Protect from Light 是的 Packaged under inert gas 是的 Cell permeable 是的 Purity ≥98% by HPLC Chemical formula C22H20N4O CAS number 545380-34-5 Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. Storage +2°C to +8°C Ship Ambient Temperature Only Toxic
