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NDGA|正品进口
产品信息
Form Crystalline solid
Primary Target LOX-5
Primary Target IC50 200 nM
Secondary target 12-LOX and 15-LOX (IC50 = 30 µM and 30 µM, respectively), cyclooxygenase (IC50 = 100 µM)
Cell permeable 是的
Purity ≥90% by HPLC
Chemical formula C18H22O4
RTECS UX1750000
CAS number 500-38-9
Merck USA index 14, 6693
Storage +15°C to +30°C
Ship Ambient Temperature Only
Harmful
产品说明
A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC50 = 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC50 = 100 µM). Also shown to inhibit platelet-derived growth factor (PDGF)-stimulated DNA synthesis in Swiss/3T3 cells. A powerful hydroxy radical quencher. |