|
(+)-MK 801 Maleate
(5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5-10-imine, Maleate, Dizocilpine Maleate, NMDA Antagonist I
A highly potent, selective, and non-competitive NMDA receptor antagonist that acts by binding to a site located within the NMDA-associated ion channel, thus preventing Ca2+ flux. An effective anti-ischemic agent in several animal models. Has been used to develop an in vivo model of NMDA receptor-dependent apoptotic neurodegenerative disease in developing rat brains. Has also been used to develop an in vitro model of NMDA receptor-specific Ca2+ entry induced seizures.
产品信息
Form White solid
Molar mass 337.4
Protect from Moisture 是的
Purity ≥98% by HPLC
Solubility EtOH or H2O
Chemical formula C16H15N · C4H4O4
CAS number 77086-22-7
Merck USA index 14, 3386
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |