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产品信息
A cell-permeable synthetic steroid that acts as a potent antagonist of progesterone and glucocorticoid receptors. Inhibits P-glycoprotein (P-gp) function and down-modulates P-gp mediated drug resistance. Displays anti-angiogenic effects and suppresses vascular endothelial growth factor (VEGF) production. Regulates the expression of Fas and FasL in mouse endometrium and TRAIL in prostate cancer cells. As an antioxidant, it offers neuroprotection against controlled cortical impact (CCI) in CA1 pyramidal cells, as well as Aβ-, H2O2-, and glutamate-induced injury to mouse hippocampal HT22 cells.
CAS number 84371-65-3
Merck USA index 14, 6186
Storage +2°C to +8°C
Form Yellow solid
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥99% by titration
Contaminants Steroid substances: ≤0.1%
Chemical formula C29H35NO2
RTECS KG2955000 |