Melittin A 26-residue polypeptide from bee venom that binds calmodulin in a Ca2+-dependent manner. A stimulator of Giα and G11α activity that is reported to inhibit adenylate cyclase activity in synaptic membranes. Activates phospholipase A2 and inhibits protein kinase C (IC50 = 5-7 µM) by binding to the catalytic domain in a Mg2+-ATP sensitive manner. Has also been used for affinity purification of several Ca2+-binding proteins. 产品信息 Peptide Sequence H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 Form Lyophilized Primary Target PKC Primary Target IC50 5-7 µM Molar mass 2846.5 Purity >97% by HPLC Sold on the basis of peptide content 是的 Solubility H2O Chemical formula C131H229N39O31 RTECS OS3960000 CAS number 37231-28-0 Merck USA index 14, 5824 商店和运输信息 Storage -20°C Ship Ambient Temperature Only Standard Handling