产品信息
Peptide Sequence H-Cys¹-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys¹0-OH (cyclic: 1→ 10)
Form White lyophilized solid
Formulation Supplied as a trifluoroacetate salt.
Primary Target MMP-2, MMP-9
Primary Target IC50 10 µM
Hygrocopic 是的
Packaged under inert gas 是的
Purity ≥97% by HPLC
Chemical formula C52H71N13O14S2
Declaration Sold under license of U.S. Patent 6,624,144.
Storage -20°C
A hydrophobic cyclic peptide that acts as a potent inhibitor of MMP-2 and MMP-9 (IC50 = 10 µM). Inhibits the migration of human endothelial cells and tumor cells, and prevents tumor growth and invasion in animal models. Also, phage that display this peptide specifically targets angiogenic blood vessels in vivo. |