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MMP-8, Human Neutrophil
Matrix Metalloproteinase 8, Human Neutrophil Collagenase, Collagenase-2
Native pro-MMP-8 from stimulated human neutrophils. MMP-8 is an N-linked, complex glycoprotein that preferentially hydrolyzes Type I collagen versus Types II and III. Activated MMP-8 is inhibited by TIMP-1. Requires activation just prior to use. MW 58800/44000. Note: 1 mU = 1 milliunit.
产品信息
Form Liquid
Formulation In 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl2, 1 µM ZnCl2, 0.05% BRIJ® 35 Detergent, 0.05% NaN3, pH 7.0.
Avoid freeze/thaw 是的
Specific activity ≥40 mU/mg protein
Unit definition One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol 2,4-DNP-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH per min at 37°C, pH 7.0.
Purity ≥90% by SDS-PAGE
Contaminants No other MMP activity detectable
Source Prepared from stimulated neutrophils that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
EC number 3.4.24.34
商店和运输信息
Storage ≤ -70°C
Ship Dry Ice Only
Standard Handling |