产品信息:
Form Pale yellow solid
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥95% by HPLC
Chemical formula C15H12BIO3
CAS number 562823-84-1
Storage +2°C to +8°C
Ship Ambient Temperature Only
Carcinogenic / Teratogenic
产品说明:
A cell-permeable boranyl-chalcone that binds strongly to MDM2 and irreversibly disrupts MDM2/p53 protein complex. Exhibits selective toxicity towards MDM2 overexpressing human breast cancer cell lines (IC50 = 10, 8.8, and 7 µM for MDA-MB-435, MDA-MB-231, and Wt-MCF7, respectively) compared to normal breast cell lines (IC50 = 75 and 63 µM for MCF-10A and MCF-12A, respectively).
注:本产品仅用于生命科学研究实验,不作为任何药物及其他用途。 |