正品原装|MDM2 ANTAGONIST, NUTLIN-3, RACEMIC

MDM2 Antagonist, Nutlin-3, Racemic|原装正品
产品信息： 
Form  Solid 
Protect from Light  是的 
Packaged under inert gas  是的 
Purity  ≥98% by TLC and HPLC 
Chemical formula  C30H30Cl2N4O4 
CAS number  548472-68-0 
Storage  -20°C 
Ship  Shipped with Blue Ice or with Dry Ice
Harmful 
产品说明：
A cell-permeable cis-imidazoline compound that acts as a potent and selective MDM2 antagonist (IC50 = 90 nM for Nutlin-3a and 13.6 µM for Nutlin-3b) and displays antitumor properties. Activates p53 pathway by binding MDM2 in the p53-binding pocket and inhibits MDM2-p53 interaction. Shown to suppress tumor growth by induction of apoptosis in several cancer cells with wild-type p53 and in xenografted tumor mice. A 10 mM (1 mg/172 µl) solution of MDM2 Antagonist, Nutlin-3, Racemic (Cat. No. 444151) in DMSO is also available.