产品信息： Form Reddish purple solid Primary Target soluble guanylate cyclase Primary Target IC50 2 µM Cell permeable 是的 Purity ≥98% by TLC and HPLC Chemical formula C15H10N2O2 CAS number 91300-60-6 Storage +2°C to +8°C Ship Ambient Temperature Only Harmful & Carcinogenic / Teratogenic 产品说明： A cell-permeable, competitive inhibitor of soluble guanylate cyclase (IC50 = 2 µM). Lowers the production of cGMP levels in a wide range of tissues by blocking intracellular Ca2+ release, with negligible effect on cAMP levels. Inhibits nitric oxide-induced smooth muscle relaxation. Shown to inhibit interleukin-1-induced cGMP accumulation in cultured rat aortic vascular smooth muscle cells. Also inhibits neutrophil chemotaxis induced by NO donors.