IBERIOTOXIN, B. TAMULUS, RECOM

Iberiotoxin, Buthus tamulus, Recombinant, E. coli
Recombinant Buthus tamulus iberiotoxin expressed in E. coli. Acts as a selective, reversible blocker of high conductance Ca2+-activated K+ channels (IC50 = 250 pM).
产品信息
Peptide Sequence  Pyr-Phe-Thr-Asp-Val-Asp-Cys7-Ser-Val-Ser-Lys-Glu-Cys¹3-Trp-Ser-Val-Cys¹7-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys28-Met-Gly-Lys-Lys-Cys33-Arg-Cys35-Tyr-Gln-OH (disulfide bonds: 7 →28; 13 → 35; 17 → 33)
Form  Salt-free lyophilized solid
Molar mass  4231
Biological activity  potently inhibits Ca2+-activated K+ channels expressed in Xenopus oocytes
Purity  ≥98% by HPLC
Solubility  100 mM NaCl, 10 mM Tris-HCl, pH 7.5 containing 0.1% BSA
CAS number  129203-60-7
商店和运输信息
Storage  -20°C
Ship  Ambient Temperature Only
Harmful