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HSP90 INHIBITOR, CCT018159

产品编号: 385920-5MG     查看说明书
产品名称: HSP90 INHIBITOR, CCT018159  .0   订购此产品 
供应商: Merck
规格: ***
目录价: 1,837.00
库存状态: 3周到货
CAS编号: 171009-07-7
应用范围: 生化实验
种属来源:
相关信息:

HSP90 Inhibitor, CCT018159
A cell-permeable pyrazoloresorcinol compound that inhibits HSP90 ATPase activity (IC50 = 3.2 µM and 6.6 µM against human HSP90β and yeast HSP90, respectively) by targeting the enzyme's N-terminal ATP binding site. It exhibits no detectable effects against human Hsp70 or topoisomerase II even at concentrations as high as 100 µM and inhibits a panel of 20 commonly studied kinases only at much higher concentrations. Unlike 17-AAG (Cat. No. 100068), the antitumor activity of CCT018159 is not affected by the expression of NQ01/DT-diaphorase or P-glycoprotein.
产品信息
Form  White solid
Molar mass  352.4
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥98% by HPLC
Solubility  DMSO, EtOH, or H2O
Chemical formula  C20H20N2O4
CAS number  171009-07-7
商店和运输信息
Storage  -20°C
Ship  Ambient Temperature Only
Irritant

保存条件: -20°C
说明书地址: 点击查看详细
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