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HSP90 INHIBITOR, CCT018159
产品编号: |
385920-5MG
查看说明书 |
产品名称:
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HSP90 INHIBITOR, CCT018159 .0 订购此产品 |
供应商:
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Merck |
规格: |
*** |
目录价: |
1,837.00 |
库存状态: |
3周到货 |
CAS编号:
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171009-07-7 |
应用范围: |
生化实验 |
种属来源: |
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相关信息: |
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HSP90 Inhibitor, CCT018159
A cell-permeable pyrazoloresorcinol compound that inhibits HSP90 ATPase activity (IC50 = 3.2 µM and 6.6 µM against human HSP90β and yeast HSP90, respectively) by targeting the enzyme's N-terminal ATP binding site. It exhibits no detectable effects against human Hsp70 or topoisomerase II even at concentrations as high as 100 µM and inhibits a panel of 20 commonly studied kinases only at much higher concentrations. Unlike 17-AAG (Cat. No. 100068), the antitumor activity of CCT018159 is not affected by the expression of NQ01/DT-diaphorase or P-glycoprotein.
产品信息
Form White solid
Molar mass 352.4
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥98% by HPLC
Solubility DMSO, EtOH, or H2O
Chemical formula C20H20N2O4
CAS number 171009-07-7
商店和运输信息
Storage -20°C
Ship Ambient Temperature Only
Irritant |
保存条件: |
-20°C |
说明书地址: |
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