HISTONE DEACETYLASE 3/SMRT,HIS TAG, HU

Histone Deacetylase 3, His•Tag®, Human Recombinant, S. frugiperda
This product has been discontinued.
Full-length, recombinant, human histone deacetylase 3 (HDAC3) fused at the C-terminus to a His•Tag® sequence and human SMRT (NCOR2) consisting of amino acids 395-489 fused at the N-terminus to GST and co-expressed in S. frugiperda insect cells using a baculovirus expression system. SMRT co-expression is required for full HDAC3 activity. The HDAC3-SMRT repression complex represents a novel and potentially specific therapeutic target. The purified complex is useful for the study of HDAC3 regulation and for inhibitor screening. MW: 49700 (HDAC3) and 39000 (SMRT)
产品信息
Form  Liquid
Formulation  In 138 mM NaCl, 25 mM Tris-HCl, 0.05% TWEEN®-20 detergent, 10% glycerol, pH 8.0.
Molar mass  49700
Avoid freeze/thaw  是的
Specific activity  ≥110 units/µg protein
Unit definition  One unit is defined as the amount of enyme that is required to deacetylate 1 pmol fluorescent peptide substrate [Arg-His-Lys-Lys(Ac)], per min at 37°C.
Purity  ≥90% by SDS-PAGE
商店和运输信息
Storage  ≤ -70°C
Ship  Dry Ice Only
Standard Handling