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G-418|G 418|Geneticin|G418 SULFATE, CELL CULTURE TESTED
Aminoglycoside related to gentamycin that inhibits prokaryotic and eukaryotic protein synthesis. Toxic to bacteria, yeast, protozoans, helminths, higher plant, and mammalian cells. Widely used in the selection of eukaryotic expression vectors carrying the bacterial neor/kanr genes. The product of these genes, aminoglycoside 3′-phosphotransferase, inactivates G418, neomycin, and kanamycin by phosphorylation. Introduction of either of these genes into cells can confer resistance to G418, which enables cells to grow in media containing G418. Also available as a sterile-filtered solution (Cat. No. 345812).
Alternatives
345812 G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested
Alternative products for G 418 Sulfate, Cell Culture Tested
345812 G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested
Accessories forG 418 Sulfate, Cell Culture Tested
Product information
Form White powder
Molar mass 692.7
Biological activity Assay: ≥730 µg/mg
Purity ≥98% by TLC
Contaminants Ammonia: ≤1.0%; heavy metals: ≤100 ppm
pH value 4.0 -6.0
Solubility H2O
Chemical formula C20H40N4O10 · 2H2SO4
RTECS CB9378500
CAS number 108321-42-2
Store and ship information
Storage +15°C to +30°C
Ship Ambient Temperature Only
Standard Handling |