Coagulation Factor α-XIIa, Human Plasma Native coagulation factor α-XIIa from human plasma prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation. α-XIIa is a serine protease responsible for activation of Factor XI to Factor XIa. Factor XIIa and prekallikrein are thought to be involved in a reciprocal activation mechanism whereby Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to Factor XIIa. 产品信息 Form Liquid Formulation In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3. Molar mass 80000 Avoid freeze/thaw 是的 Specific activity 50 units/mg protein (clotting assay). Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma Purity homogeneous by SDS-PAGE Source Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 商店和运输信息 Storage ≤ -70°C Ship Dry Ice Only Standard Handling