CBFβ Inhibitor 5-Ethyl-4-(4′-methoxyphenyl)-thiazolyl-2-amine, CBFα-CBFβ Inhibitor I, CBFβ-Runx1 Inhibitor I A cell-permeable thiazolyl compound that binds to CBFβ (core binding factor β) and allosterically disrupts CBFα/Runx1 binding to CBFβ both in cell-free binding studies (IC50 of ~3.5 µM by FRET and ELISA) and in HEK293 cells (IC50 of ~ 100 µM by FACS/FRET). Cellular studies indicate a good correlation between the inhibitor's antiproliferative activity and the Runx1 expression level in the target cells. 产品信息 Form Tan solid Molar mass 234.3 Protect from Light 是的 Purity ≥97% by HPLC Solubility DMSO or EtOH Chemical formula C12H14N2OS CAS number 493028-20-9 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Standard Handling 安全标示 S Phrase S: 24/25 Avoid contact with skin and eyes.