CATHEPSIN L SUBSTRATE I, FLUOROGENIC

Cathepsin L Substrate I, Fluorogenic
A tetrapeptidyl fluorogenic substrate for human cathepsin L (kcat = 20.8 sec-1, Km = 11.2 µM, and kcat/Km = 1.9 x 106 M-1 sec-1). Displays ~270-fold and ~2,500-fold greater selectivities over cathepsin B (kcat/Km = 7.0 x 103 M-1 sec-1),respectively and cathepsin K (kcat/Km = 7.6 x 102 M-1 sec-1). An excitation wavelength of 380 nm and an emission wavelength of 460 nm is recommended in order to maximize the signal of the ACC group over the background signal of uncleaved substrate. ACC = 7-Amino-4-carbamoylmethylcoumarin.
产品信息
Peptide Sequence  Ac-His-Arg-Tyr-Arg-ACC
Form  Lyophilized
Formulation  Supplied as a trifluoroacetate salt.
Molar mass  872.9
Protect from Light  是的
Hygrocopic  是的
Packaged under inert gas  是的
Purity  ≥95% by HPLC
Solubility  DMSO or 5% Acetic Acid
Chemical formula  C40H52N14O9
商店和运输信息
Storage  -20°C
Ship  Ambient Temperature Only
Standard Handling