CATHEPSIN K,HIS*TAG,HU,RECOM,E.COLI

Cathepsin K, His•Tag®, Human, Recombinant, E. coli
Cathepsin K is a member of the papain superfamily of cysteine proteinases and plays an important role in osteoclast-mediated bone resorption and collagen degradation. It is primarily expressed by osteoclasts and recent studies also suggest its expression in fibroblasts. Irregularities in cathepsin K activity, either too high or too low, contribute to osteopenic disorders such as osteoporosis and pycnodysostosis. This recombinant enzyme contains a C-terminal His•Tag® sequence. Note: 1 mU = 1 milliunit.
产品信息
Form  Liquid
Formulation  In 50 mM NaOAC, pH 5.5. The activation was stopped by addition of 10 mM MMTS, which can be removed under reducing conditions.
Molar mass  27000
Avoid freeze/thaw  是的
Specific activity  ≥900 mU/mg protein
Unit definition  One unit is defined as the amount of enzyme that will hydrolyze 0.4 µmol Z-FR-AMC per min at 37°C, pH 5.5.
Purity  ≥95% by SDS-PAGE
EC number  3.4.22.38
CAS number  94716-09-3
商店和运输信息
Storage  ≤ -70°C
Ship  Dry Ice Only
Standard Handling