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产品信息
Peptide Sequence 1-Naphthalenesulfonyl-Ile-Trp-CHO
Form Off-white solid
Primary Target cathepsin L
Primary Target IC50 1.9 nM
Cell permeable 是的
Reversible 是的
Purity ≥98% by HPLC
Chemical formula C27H29N3O4S
Storage -20°C
A potent, cell-permeable, selective, and reversible inhibitor of cathepsin L (IC50 = 1.9 nM). Also inhibits the release of Ca2+ and hydroxyproline from bone in an in vitro bone culture system and prevents bone loss in ovariectomized mice (~50 mg/kg). |