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产品信息
A tetrapeptidyl aldehyde that acts as a potent, reversible and active site binding inhibitor of caspases-3 and -7 (IC50 = 3.2 nM and 22.6 nM, respectively) and displays ~100-fold greater selectivity over caspases-8 and -9 (IC50 = 577.6 nM and 364.7 nM, respectively). Offers protection against Camptothecin (Cat. No. 208925), and anti-Fas-mediated apoptosis in Jurkat T cells.
Form White solid
CAS number 775289-20-8
Storage -20°C
Primary Target caspase-3, caspase-7
Primary Target IC50 3.2 nM, 22.6 nM
Secondary target caspase-8 (Ki = 577.6 nM), caspase-9 (Ki = 364.7 nM)
Protect from Light 是的
Packaged under inert gas 是的
Reversible 是的
Purity Single main spot with additional trace spot by TLC
Chemical formula C20H31N5O10 |