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Bongkrekic Acid, Triammonium Salt
3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic Acid, BA, 3NH4
Acts as a ligand of the adenine nucleotide translocator. A potent inhibitor of mitochondrial megachannel (permeability transition pore). Significantly reduces signs of apoptosis induced by nitric oxide. Prevents the apoptotic breakdown of the inner mitochondrial transmembrane potential (ΔΨm), as well as a number of other phenomena linked to apoptosis.
产品信息
Form Beige-pink solid
Primary Target mitochondrial mega channel
Molar mass 537.7
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥92% by HPLC
Solubility DMSO
Chemical formula C28H35O7 · 3NH4
CAS number 1177154-51-6
Merck USA index 14, 1332
商店和运输信息
Storage -20°C
Ship Dry Ice Only
Harmful & Carcinogenic / Teratogenic
安全标示
S Phrase S: 36-22
Wear suitable protective clothing.
Do not breathe dust.
R Phrase R: 20/21/22-40
Harmful by inhalation, in contact with skin and if swallowed.
Limited evidence of a carcinogenic effect. |