BLEOMYCIN SULFATE, S. VERTICILLUS

Bleomycin Sulfate, Streptomyces verticillus
Mixture of cytotoxic glycopeptides that inhibits DNA synthesis by reacting with DNA and causing strand scission. Acts by generating hydroxyl free radicals which cleave N-glycosidic bonds and cause base elimination (mainly T) and phosphodiester bond scission. An anti-neoplastic agent. Bleomycin has been used in the treatment of squamous cell carcinomas, testicular tumors, and malignant lymphomas.
产品信息
Form  White to off-white solid
Hygrocopic  是的
Biological activity  Potency: 1.5-2.0 U/mg
Purity  ≥90% by HPLC (A2 + B2)
Solubility  H2O
RTECS  EC5991990
CAS number  9041-93-4
Merck USA index 14, 1318
商店和运输信息
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Harmful & Carcinogenic / Teratogenic
安全标示
S Phrase  S: 22-26-36/37/39-45
Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
R Phrase  R: 20/21/22-36/37/38-40-42/43
Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
Limited evidence of a carcinogenic effect.
May cause sensitization by inhalation and skin contact.