Bax-Inhibiting Peptide, V5 A cell-permeable pentapeptide based on the Ku70-Bax inhibiting domain that offers cytoprotection. Functions as effectively as the Caspase Inhibitor VI (Z-VAD-FMK; Cat. No. 219007) for Bax-mediated apoptosis (~50-200 µM). Also effectively blocks caspase-independent necrotic cell death. Shown to be Ku70 competitive, interact with Bax, prevent its conformational change and mitochondrial translocation. Displays extended stability in culture medium (~3 days). Negative control peptide is also available (Cat. No. 196811). 产品信息 Peptide Sequence H-Val-Pro-Met-Leu-Lys-OH Form White lyophilized solid Formulation Supplied as a trifluoroacetate salt. Primary Target Bax mediated apoptosis Primary Target IC50 50-200 µM Molar mass 586.8 Protect from Light 是的 Hygrocopic 是的 Packaged under inert gas 是的 Cell permeable 是的 Purity ≥95% by HPLC Solubility H2O Chemical formula C27H50N6O6S 商店和运输信息 Storage -20°C Ship Blue Ice Only Standard Handling