Bax Channel Blocker (±)-1-(3,6-Dibromocarbazol-9-yl)-3-piperazin-1-yl-propan-2-ol, bis TFA, iMAC1 A cell-permeable dibromocarbazolo-piperazinyl derivative that displays anti-apoptotic properties. Effectively blocks Bid-induced cyctochrome c release from HeLa cell mitochondria (~80% inhibition at 5 µM) by inhibiting Bax channel-forming activity (IC50 = 520 nM in a liposome channel assay). 产品信息 Form Off-white solid Primary Target Bax-channel forming activity Primary Target IC50 520 nM Molar mass 695.3 Protect from Light 是的 Hygrocopic 是的 Packaged under inert gas 是的 Cell permeable 是的 Purity ≥97% by HPLC Solubility DMSO Chemical formula C19H21Br2N3O • 2CF3CO2H CAS number 335165-69-0 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Carcinogenic / Teratogenic