Autocamtide-2 Related Inhibitory Peptide II An AIP (Cat. No. 189480) analog, in which Ala3 and Val10 are replaced with Lys and Phe respectively. Acts as a highly specific, potent inhibitor of calmodulin-dependent protein kinase II (CaMKII; IC50 = 4.1 nM). Displays ~10-fold greater potency than AIP. Inhibits PKC at higher concentrations (IC50 = 1 µM) and does not affect the activities of CaMK IV and PKA (IC50 > 100 µM). 产品信息 Peptide Sequence H-Lys-Lys-Lys-Leu-Arg-Arg-Gln-Glu-Ala-Phe-Asp-Ala-Leu-OH Form White lyophilized solid Formulation Supplied as a trifluoroacetate salt. Primary Target CAM Kinase-2 Primary Target IC50 4.1 nM Secondary target PKC (IC50 = 1 µM) Molar mass 1602.9 Hygrocopic 是的 Packaged under inert gas 是的 Purity ≥97% by HPLC Solubility DMSO Chemical formula C71H123N23O19 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Standard Handling